abstract：OBJECTIVE:To define the mechanisms of the stable and prolonged post-operative plasma volume expansion observed with Hydroxyethyl Starches (HES) and to determine whether a partial intravascular hydrolysis of large molecules contribute to reinforce the colloid-osmotic effect. DESIGN:Prospective, pharmacologic study usin...

journal_title：Intensive care medicine

authors： Degrémont AC,Ismaïl M,Arthaud M,Oulare B,Mundler O,Paris M,Baron JF

更新日期：1995-07-01 00:00:00

abstract：OBJECTIVE:Percutaneous dilatational tracheostomy is increasingly practiced in intensive care units and has a low incidence of early complications. The late effects of this procedure are still poorly known and were the focus of this study. DESIGN:Prospective descriptive clinical study. SETTING:Interdisciplinary intens...

journal_title：Intensive care medicine

authors： Fischler MP,Kuhn M,Cantieni R,Frutiger A

更新日期：1995-06-01 00:00:00

abstract：OBJECTIVE:To evaluate a least squares fitting technique for the purpose of measuring total respiratory compliance (Crs) and resistance (Rrs) in patients submitted to partial ventilatory support, without the need for esophageal pressure measurement. DESIGN:Prospective, randomized study. SETTING:A general ICU of a Univ...

journal_title：Intensive care medicine

authors： Iotti GA,Braschi A,Brunner JX,Smits T,Olivei M,Palo A,Veronesi R

更新日期：1995-05-01 00:00:00

abstract：OBJECTIVE:To explore translation, conversion and definition ambiguities, when using severity scoring systems in patients admitted to intensive care units (ICUs). DESIGN:A prospective study of the prognosis of acute renal failure in ICUs. SETTING:The study was conducted in 20 French ICUs. PATIENTS:360 patients presen...

journal_title：Intensive care medicine

authors： Féry-Lemonnier E,Landais P,Loirat P,Kleinknecht D,Brivet F

更新日期：1995-04-01 00:00:00

abstract：OBJECTIVE:To describe Enterococcus faecalis colonisation and endocarditis in 5 intensive care patients after treatment with selective decontamination (SDD). SETTING:Intensive care unit (ICU) in a general hospital. PATIENTS:The patients were admitted to the ICU because of adult respiratory distress syndrome, polytraum...

journal_title：Intensive care medicine

authors： Sijpkens YW,Buurke EJ,Ulrich C,van Asselt GJ

更新日期：1995-03-01 00:00:00

abstract：:The process of fluidisation involves blowing warm air through small solid microspheres thus creating a liquid, without wetness. The warmth provides some important properties including reducing the metabolic rate in thermal injury which has a beneficial effect on mortality, modifying catabolism after surgery, providing...

journal_title：Intensive care medicine

authors： Ryan DW

更新日期：1995-03-01 00:00:00

abstract：OBJECTIVE:Hospital mortality of patients with septic multiorgan failure (MOF) is still around 95%. The present study investigates whether this high mortality could be significantly reduced by the addition of sequential hemofiltration (SH) with bicarbonate hemodialysis (HD) to the currently used life supportive measures...

journal_title：Intensive care medicine

authors： Gotloib L,Shostak A,Lev A,Fudin R,Jaichenko J

更新日期：1995-02-01 00:00:00

abstract：:Central venous catheters (CVCs) are widely used in critically ill patients in intensive care units. However, infectious complications are common and may limit their utility. We critically review the literature to determine the impact of CVC design and composition, insertion site selection, insertion procedures, care a...

journal_title：Intensive care medicine

authors： Reed CR,Sessler CN,Glauser FL,Phelan BA

更新日期：1995-02-01 00:00:00

abstract：:A 46-year-old man was diagnosed clinically brain dead after sustaining head trauma. The patient was in deep coma, brain nerves were unresponsive and spontaneous breathing was absent. However, EEG showed well preserved activity, but no reactivity to external stimuli. EEG activity disappeared within 40 h. BAEP were high...

journal_title：Intensive care medicine

authors： Kaukinen S,Mäkelä K,Häkkinen VK,Martikainen K

更新日期：1995-01-01 00:00:00

abstract：:Diagnosis and treatment of infection is a common procedure in the clinical management of patients in the ICU. Infection in the ICU is an important area for study, but requires well-defined and proven diagnostic criteria. The diagnosis of infection, like any diagnosis, is based on probability, and diagnostic criteria a...

journal_title：Intensive care medicine

authors： Langer M,Pifferi S,Peta M

更新日期：1994-11-01 00:00:00

abstract：OBJECTIVE:To evaluate the efficiency of a new device developed to remove obstructions from endotracheal tubes (ETT) in mechanically ventilated patients. DESIGN:Open study in mechanically ventilated sedated and paralyzed ICU patients. SETTING:General ICU and Laboratory of Respiratory Mechanics of the University of Rom...

journal_title：Intensive care medicine

authors： Conti G,Rocco M,De Blasi RA,Lappa A,Antonelli M,Bufi M,Gasparetto A

更新日期：1994-11-01 00:00:00

abstract：OBJECTIVE:To report the first case of ARDS in children treated with nitric oxide (NO) inhalation. METHODS:A 13-months infant presented with BPD and severe hypoxemia related to RSV infection and ARDS. Inhaled NO was delivered in the ventilatory circuit of a continuous flow ventilator (Babylog 8000, Dräger) in a concent...

journal_title：Intensive care medicine

authors： Leclerc F,Riou Y,Martinot A,Storme L,Hue V,Flurin V,Deschildre A,Sadik A

更新日期：1994-08-01 00:00:00

abstract：:Production of beta-lactamases is the most important means of bacterial resistance to beta-lactam antibiotics. The traditional, plasmid-mediated beta-lactamases were initially confined to Enterobacteriaceae but have now spread to other genera and species including Pseudomonas aeruginosa, Haemophilus influenzae, and Nei...

journal_title：Intensive care medicine

authors： Garau J

更新日期：1994-07-01 00:00:00

abstract：:We report the case of a 72-year-old male who suffered a cardiac arrest during an early positive treadmill stress test. After successful resuscitation the patient had evidence of a gastric perforation. Because of his hemodynamic stability, lack of peritoneal signs, and prohibitively high surgical risk, a non-operative ...

journal_title：Intensive care medicine

authors： Low LL,Ripple GR,Bruderer BP,Harrington GR

更新日期：1994-07-01 00:00:00

abstract：OBJECTIVE:To test the hypothesis whether PMN-Elastase in bronchoalveolar lavage fluid (BALF) could reflect neutrophil activity in the lower respiratory tract. DESIGN:Prospectively, morphologic findings of acute and chronic inflammation in the transbronchial lung biopsy specimens were compared with the numbers of neutr...

journal_title：Intensive care medicine

authors： Lengas A,Poletti V,Pacifico L,di Domizio C,Patelli M,Spiga L

更新日期：1994-05-01 00:00:00

abstract：:We examined the incidence, diagnosis and therapy of acute adrenal insufficiency, secondary to adrenal hemorrhage. This insufficiency resulted in temperature irregularities. hemodynamic instability, and a large volume resuscitation requirement post-operatively. The case illustrates that a high level of suspicion should...

journal_title：Intensive care medicine

authors： Szalados JE,Vukmir RB

更新日期：1994-01-01 00:00:00

abstract：OBJECTIVE:To determine the magnitude and time course of adrenergic effects on metabolism in volunteers and possible implications for the use of sympathomimetics in the critically ill. DESIGN:Descriptive laboratory investigation. SUBJECTS:7 volunteers. INTERVENTION:Primed continuous infusions of stable isotope tracer...

journal_title：Intensive care medicine

authors： Ensinger H,Träger K,Geisser W,Anhäupl T,Ahnefeld FW,Vogt J,Georgieff M

更新日期：1994-01-01 00:00:00

abstract：:A 29-year-old woman was admitted to the Rouen University Hospital for attempted suicide by ingestion of a carbamate insecticide (Temik G, containing 10% aldicarb). Cardio-respiratory arrest occurred at the second hour and acute necrotic hemorrhagic pancreatitis on the second day. Further evolution was uneventful, and ...

journal_title：Intensive care medicine

authors： Moritz F,Droy JM,Dutheil G,Melki J,Bonmarchand G,Leroy J

更新日期：1994-01-01 00:00:00

abstract：:Status epilepticus is one of the most frequent neurological emergencies in the intensive care unit. Standard treatment includes intravenous barbiturates, benzodiazepines and phenytoin. However, drug coma is sometimes necessary to control refractory status epilepticus. We report such a case, successfully treated by int...

journal_title：Intensive care medicine

authors： Borgeat A,Wilder-Smith OH,Jallon P,Suter PM

更新日期：1994-01-01 00:00:00

abstract：OBJECTIVE:To present the efficacy and tolerability of a new oral dosage form of the calcium antagonist nitrendipine compared to nifedipine capsules in patients with hypertensive emergency. DESIGN:Multicenter randomized double blind clinical study. SETTING:23 study centres (hospitals) in Germany. PATIENTS:161 patient...

journal_title：Intensive care medicine

authors： Rohr G,Reimnitz P,Blanke P

更新日期：1994-01-01 00:00:00

abstract：OBJECTIVES:To investigate at what time the peak level should be determined under conventional thrice daily (t.i.d.) administration of the aminoglycoside netilmicin and to study its serum concentrations under once daily (od) treatment to define the required daily dose and to gain information about convenient drug monito...

journal_title：Intensive care medicine

authors： Konrad F,Wagner R,Neumeister B,Rommel H,Georgieff M

更新日期：1993-01-01 00:00:00

abstract：:During the last two decades, severe group A beta-haemolytic streptococcal infections have been defined as the "toxic strep syndrome", and have been reported not only in immunocompromised or elderly people, but also occasionally in previously healthy patients. We describe 4 patients presenting with the toxic strep synd...

journal_title：Intensive care medicine

authors： Soravia C,Romand JA,Herrmann M,Chevrolet JC,Ricou B,Suter PM

更新日期：1993-01-01 00:00:00

abstract：:Several different epidemiological typing methods have been used in studies of coagulase-negative staphylococci; these include biotyping, antibiotic susceptibility pattern analysis, serological typing, phage typing, slime production detection, protein profile analysis, immunoblot fingerprinting and DNA typing. The most...

journal_title：Intensive care medicine

authors： Vandenesch F,Lina B,Lebeau Ch,Greenland TB,Etienne J

更新日期：1993-01-01 00:00:00

abstract：:We present a patient with evidence of severe intravascular hemolysis after mitral valve repair, an established method for the surgical treatment of mitral valve disease to avoid prosthesis related complications. The coincidence of this uncommon complication with hemodynamic instability due to pre-existing myocardial d...

journal_title：Intensive care medicine

authors： Seyr M,Hasibeder W,Furtwaegler W,Antretter H,Mutz NJ

更新日期：1993-01-01 00:00:00

abstract：OBJECTIVE:To compare haemodynamic and gas exchange effects after either atracurium or pancuronium given to ventilated neonates with respiratory failure. DESIGN:In this prospective study neonates were alternately assigned to receive either atracurium or pancuronium, intravenously. SETTING:Paediatric and neonatal ICU i...

journal_title：Intensive care medicine

authors： Piotrowski A

更新日期：1993-01-01 00:00:00

abstract：OBJECTIVE:An investigation into the incidence of post-operative complications after thoracic surgery with 3 different physiotherapy masks. DESIGN:A prospective, consecutive, randomized comparison. SETTING:Department of Thoracic and Heart Surgery at a University Hospital. The treatments were performed by experienced a...

journal_title：Intensive care medicine

authors： Ingwersen UM,Larsen KR,Bertelsen MT,Kiil-Nielsen K,Laub M,Sandermann J,Bach K,Hansen H

更新日期：1993-01-01 00:00:00

abstract：:In severe status asthmaticus basic medical treatment often fails to improve the patient's condition. Mechanical ventilation in this situation is associated with a high incidence of serious complications. After the bronchodilating effect of moderate-dose magnesium sulfate in asthmatic patients had been demonstrated in ...

journal_title：Intensive care medicine

authors： Sydow M,Crozier TA,Zielmann S,Radke J,Burchardi H

更新日期：1993-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the sensitivity, specificity and overall accuracy of a model based on the presence or absence of organ dysfunctions and/or infection (ODIN) to predict the outcome for intensive care unit patients. DESIGN:Prospective study. SETTING:General intensive care unit in a university teaching hospital. P...

journal_title：Intensive care medicine

authors： Fagon JY,Chastre J,Novara A,Medioni P,Gibert C

更新日期：1993-01-01 00:00:00

abstract：OBJECTIVE:To determine what change in respiratory function occurred following prolonged and efficient continuous arteriovenous haemofiltration (CAVH) in a group of patients with multiple organ systems failure (MOSF). DESIGN:A retrospective assessment using patient notes and ICU charts. SETTING:The Intensive Care Unit...

journal_title：Intensive care medicine

authors： Bagshaw ON,Anaes FR,Hutchinson A

更新日期：1992-01-01 00:00:00

abstract：OBJECTIVE:To compare isoflurane with midazolam for prolonged sedation in ventilated patients. DESIGN:Randomised controlled study. SETTING:General intensive care unit in university teaching hospital. PATIENTS:Sixty patients aged 17-80 years who required mechanical ventilation for more than 24 h. INTERVENTIONS:Sedati...

journal_title：Intensive care medicine

authors： Spencer EM,Willatts SM

更新日期：1992-01-01 00:00:00

abstract：:Nosocomial pneumonia continues to represent a significant cause of morbidity and mortality in hospitalized patients. Bacteria are responsible for greater than 90% of the pneumonias, the most common isolates being aerobic Gram-negative bacilli and S. aureus. Cornerstones of treatment are intravenous antibiotics and sup...

journal_title：Intensive care medicine

authors： Unertl KE,Lenhart FP,Forst H,Peter K

更新日期：1992-01-01 00:00:00

abstract：:A study was conducted to evaluate repeated intrathecal injections of baclofen, without artificial ventilation, in the treatment of severe tetanus. Ten patients, 5 men and 5 women, with a mean age of 34 +/- 7 years, were included in the study. The dose of baclofen injected was 1000 micrograms between the ages of 16 and...

journal_title：Intensive care medicine

authors： Saissy JM,Demazière J,Vitris M,Seck M,Marcoux L,Gaye M,Ndiaye M

更新日期：1992-01-01 00:00:00

abstract：OBJECTIVE:The purpose of the study was do describe the architecture of accretions occurring on the tips of central venous catheters (CVC). DESIGN:A conservative procedure was used followed by two different techniques of electron microscopy. SETTING AND PATIENTS:the study included 19 catheters which have been used on ...

journal_title：Intensive care medicine

authors： Poisson DM,Touquet S,Bercault N,Arbeille B

更新日期：1992-01-01 00:00:00

abstract：:Sixteen anaesthetized rabbits were subjected to tracheostomy and lung damage produced by the instillation of 4.5 ml/kg hydrochloric acid (pH 1.5) into the trachea. Half of the animals were ventilated with a positive end-expiratory pressure (PEEP) of 3 cmH2O and half with a PEEP of 10 cmH2O for 5 h, the mean airway pre...

journal_title：Intensive care medicine

authors： Sohma A,Brampton WJ,Dunnill MS,Sykes MK

更新日期：1992-01-01 00:00:00

abstract：:Type III procollagen N-peptides (PIIINPs) are believed to be released in stoichiometric amounts as type III collagen molecules are secreted from cells. We hypothesized that if the human lung actively produces type III collagen a detectable transpulmonary gradient in PIIINPs would exist in normal individuals that might...

journal_title：Intensive care medicine

authors： Harrison NK,Laurent GJ,Evans TW

更新日期：1992-01-01 00:00:00

abstract：:A total of 6178 persons with out-of-hospital (70%) and in hospital (30%) cardiac arrests from the first of January 1982 until the end of 1989 were reviewed retrospectively with respect to 4 variables, contributing to a score for specific prediction of poor prognosis (cut-off point: greater than 3 points). These includ...

journal_title：Intensive care medicine

authors： Martens PR,Mullie A,Buylaert W,Calle P,van Hoeyweghen R

更新日期：1992-01-01 00:00:00

abstract：:A case of bilateral pseudoaneurysms of the pulmonary arteries caused by blunt chest injury is presented. Although this is a very rare complication, this entity should always be suspected in a patient with hemoptysis and a radiodensity on chest radiograph following chest injury. Selection of operative procedures should...

journal_title：Intensive care medicine

authors： Kasai T,Kobayashi K

更新日期：1992-01-01 00:00:00

abstract：:Myxoedema coma is a medical emergency with high mortality. In this study, clinical response and plasma variations of thyroid hormones were analysed in 7 patients, 6 presenting with myxoedema coma and one with myxoedema ileus. These patients were treated with intravenous or oral l-thyroxine (l-T4). 1000 mu l-T4 iv were...

journal_title：Intensive care medicine

authors： Arlot S,Debussche X,Lalau JD,Mesmacque A,Tolani M,Quichaud J,Fournier A

更新日期：1991-01-01 00:00:00

abstract：:The pharmacokinetics of theophylline and ethylenediamine were examined in 6 patients with septicaemia and multiorgan failure (MOF). The patients received a bolus injection of 4 mg/kg aminophylline. Aminophylline is the ethylenediamine salt of theophylline. The clearance of theophylline was reduced in all our patients ...

journal_title：Intensive care medicine

authors： Toft P,Heslet L,Hansen M,Klitgaard NA

更新日期：1991-01-01 00:00:00

abstract：:A randomized study of 30 patients undergoing uncomplicated surgery under spinal anesthesia was conducted to assess the influence of colloids on the kinetics of plasma fibronectin and complement. Both are opsonins of the reticuloendothelial system; moreover fibronectin is concerned with host resistance against septic c...

journal_title：Intensive care medicine

authors： Vedrinne JM,Hoen JP,Bussery D,Veyssere C,Richard M,Motin J

更新日期：1991-01-01 00:00:00